Estrogen and progesterone receptor status and outcome in epithelial ovarian cancers and low malignant potential tumors
نویسندگان
چکیده
منابع مشابه
Estrogen and progesterone receptors in ovarian epithelial tumors.
Epidemiological studies have indicated a relationship between ovarian cancer and gonadal steroid hormones. In the present study immunohistochemical localization in combination with morphometry were used to characterize changes in the pattern of expression for estrogen receptor alpha (ERalpha), estrogen receptor beta (ERbeta), and progesterone receptor (PR), in epithelial cells of normal ovaries...
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background : this study evaluates estrogen and progesterone expressions in patients with ovarian tumors (both benign and malignant) and their correlation with various clinicopathological prognostic parameters. receptors for estrogen and progesterone are predictive and prognostic markers of endometrial and breast cancers. however, their clinical significance in epithelial ovarian cancer is not c...
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Ovarian carcinoma (OCa) continues to be the leading cause of death due to gynecologic malignancies and the vast majority of OCa is derived from the ovarian surface epithelium (OSE) and its cystic derivatives. Epidemiological evidence strongly suggests that steroid hormones, primarily estrogens and progesterone, are implicated in ovarian carcinogenesis. However, it has proved difficult to fully ...
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The article by Trimble and Trimble nicely summarizes the state of knowledge on ovarian tumors of low malignant potential (LMP) and underscores the fact that gaps in that knowledge have led to confusion and controversy regarding several issues related to these interesting neoplasms. Many of these controversies can be characterized as debates between the "lumpers" and the "splitters.' The Johns H...
متن کاملOvarian tumors of low malignant potential.
Clinical and laboratory reports suggest that ovarian tumors of low malignant potential (LMP) represent a "grab bag" of tumors, with different etiologies, molecular biologies, and prognoses. As a result, data on incidence and prognosis may be quite unreliable. Diagnosis is best made on permanent section. Half of women under age 40 undergo conservative, fertility-sparing surgery when diagnosed wi...
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ژورنال
عنوان ژورنال: Gynecologic Oncology
سال: 2009
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2009.05.045